I recently received a diagnosis of Crohn's disease. I've had 1.5 years of GI pain and loose stools with occasional bleeding, etc. I have since had a colonoscopy that appeared normal, however terminal ileum biopsy was positive for acute inflammation. Therefore, prometheus IBD labs were ordered. These came back positive for Crohn's. I had MRE done (which showed no significant inflammation) so I had the prometheus MONITR test done which showed moderate activity.
I am now with a second doctor for a second opinion regarding treatment options. They are favoring immunologic drugs, however they want to repeat colonoscopy because they need to confirm moderate disease before insurance will cover medications. We have also discussed pillCam. Anyone with experience of essentially normal MRE test and visually normal colonoscopy, but then had repeat scope or pillCam that showed disease? Just trying to decide if I should go through more tests or consider budesonide before immunologics. I did have improvement of symptoms with prednisone taper (but not a long term solution), but no response to Apriso. Thanks for your help!