I HATE IT when the weather changes!!!! I use to be able to handle when it got to hot or cold but now if I get to hot from the heat or to cold from the weather my Crohn's Disease goes into overdrive and I get so sick and it usually takes me about a week or two to get straightened back out. But if it's to warm outside it's best I just stay at home in my air conditioned house. The cold weather I can deal with a lot better because if I get to cold I can warm back up and be fine. It's bad what us with IBD diseases go through and hopefully one day there will be a cure and no else will have to go through what we do!!!!