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New diagnosis- Mesalazine and Budesonide enemas

I have been suffering from rectal bleeding and bowel urgency since I gave birth to my son 14 months ago, I was initially diagnosed with haemorrhoids on a colonoscopy and had them banded twice with no improvement, i them went back to my doctor as I felt my symptoms were more than just haemorrhoids as I was getting leakage on passing gas and a lot of what I’d describe as a watery brownish fluid before each bowel movement but stools after this are normal. I was referred for another colonoscopy and had multiple biopsies taken approx 4-5 weeks ago, the doctor said it was ulcerative colitis, he showed me the inflammation on the screen and prescribed Octasa (Mesalazine) and Budenofalk enemas. I have to admit I have not started any of these medications yet as I’m worried about side effects and was waiting for my biopsy results to come back first. I rang to chase results this week and they are running very behind due to Covid delays. I am unsure whether to start the meds or wait for results. What are peoples experiences of these meds and do my symptoms sound normal for UC?

Many thanks

  1. I'm so sorry to read about your rectal bleeding and bowel urgency. As one with UC, I deal with both issues often. I haven't taken "Octasa," but I have taken other mesalazine forms such as Pentasa and Canasa. Honestly, I've had the most success with Canasa. It seemed to work the quickest on my body, but that's because it comes in suppository form. My colitis is mainly found in the rectum and descending colon region. So, the suppository seems to "hit the spot" best. (Sorry about the pun.) I find the suppository easier to use when traveling, too. Personally, I've never liked the "enema" versions of mesalazine. Once I was prescribed Rowasa (enema), and I didn't find it very convenient for my body. I didn't particularly like dealing with a liquid form of medicine. My body responds well to Canasa. But each person's body is different. The only side effects I experience when on it are fatigue (but that might be more from the rectal bleeding) and some bloating. Also, if I take it for too long, I begin to get headaches. So, I usually am on it for shorter stints. I'm no trained physician, so, I can't really tell you whether to begin or not. All I can share is how my body responded to the mesalazine prescription. I think if your UC symptoms are interfering with your quality of life, then that should weigh into your decision. Ultimately, you know your body best. What I've learned most about UC in this forum is how each person's body responds differently to treatments. So, whatever you choose to do, don't give up on treatment. Sometimes it may take a while (through trial and error) to find the BEST prescriptive path for your body. I hope this helps. Not sure if I offered any useful information. Please keep in touch and let us know how your journey goes. On the positive side, at least you know what is causing the bleeding and urgency. Now, it's just a matter of finding the right treatment for you. Hope you're having a good day. Hugs! --Traci (UC-IBD Team Member)

    1. That definitely sounds like UC. I understand your hesitation with starting the medication. For me personally, meds have helped me tremendously to get symptoms under control. Perhaps give it a try and if you get symptoms then you can stop? Sending strength your way, Elizabeth (team member)

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