I hear you. In my personal journey, I went from Mesalamine to Remicade to Entyvio then into Humira, Stelara which are injections, then into pills Xeljanz, Rinvoq, now back to an injection called Skyrizi. Each of my transitions were different. I will say going from Stelara to Xeljanz was my best transition. When I started taking Xeljanz I almost instantly felt better. I was on it for about 2.5 years. I guess what I want to share is that it is definitely do-able to transition into a new medicine. If you are wanting to explore a different treatment, let your doctor know as there are many out there. Perhaps express you no longer want to do a biologic and would like to try a different class of drug like a JAK Inhibitor. -Elizabeth (team member)