I am 67 and have been taking Xeljanz for about 2 years. I have RA and ulcerative colitis. My UC has been in remission for about 7 years. I have been having what my GI doctor thinks is IBS. I have been nearly debilitated by lower abdominal pain. Taking dicyclomine 4 times a day helps somewhat. Has anyone else developed IBS after starting or after taking Xeljanz for a period of time? I saw there currently is a study showing an increased incidence of IBS in people, especially women over the age of 60, who are taking Xeljanz.