Hi I have gone through many different brands of probiotics and other people I have talked to about them have also gone through many. I think the problem is that with IBD everyone is different and not all probiotics work for everyone. I personally don't use them anymore, due to expense and could not find one that worked, but from others I have talked to, probiotics with Lactobacillus acidophilus worked the best and just that, nothing added. Vern - IBD Team Member