Stressed induced flare up?

My husband has Chrohn’s and a very stressful job. For a while now, he’ll randomly experience episodes of extreme fatigue, diarrhea, and nausea to the point where he will go almost an entire day or two without eating. The symptoms seem to mostly occur when the stress is really high and then a weekend comes and he’s able to come down from stress. I’m wondering if anyone else has ever experienced this or if it’s seemingly normal in people with Chrohn’s?