Can prednisone cause weight gain?

Yes, between fluid retention and increase in appetite.

Thank you for your question and thank you for the answer !
https://inflammatoryboweldisease.net/living/the-prednisone-made-me-do-it/

Please keep us posted!

- Susan (InflammatoryBowelDisease.net Team Member)

Hi Jb68!

Yes it can. But it doesn't always. I never gained weight while on Prednisone. Ever! Almost everyone I've known has either gained weight or had the infamous, moon face.

Again, everyone reacts differently to treatment.

-Brooke
(inflammatoryboweldisease.net Team Member)