caret icon Back to all discussions

GLP-1 Weight loss and IBS

Hi,
I have both IBS and ischemic colitis and I am very obese. I’m curious if anyone who also has IBS is currently taking GLP-1. And if so what side effects do you experience and how are you doing with taking the medication for weight loss. I am currently not taking GLP-1 but interested in looking into it.
Thanks for your help with my questions.

  1. Hi . Because IBD is an inflammatory autoimmune condition it is entirely possible that the interaction and effectiveness for GLP-1s will be different than it is for IBS. There is research finding that, for IBD, GLP-1s may be effective for weight loss, as well as potentially helping reduce intestinal inflammation, thus helping with disease activity (see: https://www.gastroendonews.com/Inflammatory-Bowel-Disease/Article/10-24/GLP-1-IBD-obesity-inflammatory-bowel-disease/75152). There is also some evidence in improvements for IBS (see: https://pmc.ncbi.nlm.nih.gov/articles/PMC11932899/). I want to note that we have a sister-site for IBS at https://irritablebowelsyndrome.net/. You may want to check in there to see if anyone has additional insight. Wishing you the best. Richard (Team Member)

Please read our rules before posting.